Anti-Muggle pranksters,’ said Mr. Weasley, frowning. ‘We had two last week, one in Wimbledon, one in Elephant and Castle. Muggles are pulling the flush and instead of everything disappearing—well, you can imagine. The poor things keep calling in those—pumbles, I think they're called—you know, the ones who mend pipes and things.’
‘Plumbers?’
‘—exactly, yes, but of course they're flummoxed. I only hope we can catch whoever's doing it.’
‘Will it be Aurors who catch them?’
‘Oh no, this is too trivial for Aurors, it'll be the ordinary Magical Law Enforcement Patrol—ah, Harry, this is Perkins.’
A stooped, timid-looking old wizard with fluffy white hair had just entered the room, panting.
‘Oh, Arthur!’ he said desperately, without looking at Harry. ‘Thank goodness, I didn't know what to do for the best, whether to wait here for you or not. I've just sent an owl to your home but you've obviously missed it—an urgent message came ten minutes ago—’
‘I know about the regurgitating toilet,’ said Mr. Weasley.
‘No, no, it's not the toilet, it's the Potter boy's hearing—they've changed the time and venue—it starts at eight o'clock now and it's down in old Courtroom Ten—’
‘Down in old— but they told me—Merlin's beard—’
Mr. Weasley looked at his watch, let out a yelp and leapt from his chair.
‘Quick, Harry, we should have been there five minutes ago!’
Perkins flattened himself against the filing cabinets as Mr. Weasley left the office at a run, Harry close on his heels.
‘Why have they changed the time?’ Harry said breathlessly, as they hurtled past the Auror cubicles; people poked out their heads and stared as they streaked past. Harry felt as though he had left all his insides back at Perkins's desk.
‘I've no idea, but thank goodness we got here so early, if you'd missed it, it would have been catastrophic!’
Mr. Weasley skidded to a halt beside the lifts and jabbed impatiently at the ‘down’ button.
‘Come ON!’
The lift clattered into view and they hurried inside. Every time it stopped Mr. Weasley cursed furiously and pummelled the number nine button.
‘Those courtrooms haven't been used in years,’ said Mr. Weasley angrily. ‘I can't think why they're doing it down there—unless—but no...’
A plump witch carrying a smoking goblet entered the lift at that moment, and Mr. Weasley did not elaborate.
‘The Atrium,’ said the cool female voice and the golden grilles slid open, showing Harry a distant glimpse of the golden statues in the fountain. The plump witch got out and a sallow-skinned wizard with a very mournful face got in.
‘Morning, Arthur,’ he said in a sepulchral voice as the lift began to descend. ‘Don't often see you down here....’
‘Urgent business, Bode,’ said Mr. Weasley, who was bouncing on the balls of his feet and throwing anxious looks over at Harry.
‘Ah, yes,’ said Bode, surveying Harry unblinkingly. ‘Of course.’
Harry barely had emotion to spare for Bode, but his unfaltering gaze did not make him feel any more comfortable.
‘Department of Mysteries,’ said the cool female voice, and left it at that.
‘Quick, Harry,’ said Mr. Weasley as the lift doors rattled open, and they sped up a corridor that was quite different from those above. The walls were bare; there were no windows and no doors apart from a plain black one set at the very end of the corridor. Harry expected them to go through it, but instead Mr. Weasley seized him by the arm and dragged him to the left, where there was an opening leading to a flight of steps.
‘Down here, down here,’ panted Mr. Weasley, taking two steps at a time. ‘The lift doesn't even come down this far ... why they're doing it down there...’
They reached the bottom of the steps and ran along yet another corridor, which bore a great resemblance to the one that led to Snape's dungeon at Hogwarts, with rough stone walls and torches in brackets. The doors they passed here were heavy wooden ones with iron bolts and keyholes.
‘Courtroom ... ten ... I think ... we're nearly ... yes.’
Mr. Weasley stumbled to a halt outside a grimy dark door with an immense iron lock and slumped against the wall, clutching at a stitch in his chest.
‘Go on,’ he panted, pointing his thumb at the door. ‘Get in there.’
‘Aren't—aren't you coming with—?’
‘No, no, I'm not allowed. Good luck!’
Harry's heart was beating a violent tattoo against his Adam's apple. He swallowed hard, turned the heavy iron door handle and stepped inside the courtroom.
Monday, November 15, 2010
Sunday, November 14, 2010
‘You're not telling me you enjoyed it
?’ Ron said quietly, turning a glazed face towards Hermione. ‘That was about the dullest speech I've ever heard, and I grew up with Percy.’
‘I said illuminating, not enjoyable,’ said Hermione. ‘It explained a lot.’
‘Did it?’ said Harry in surprise. ‘Sounded like a load of waffle to me.’
There was some important stuff hidden in the waffle,’ said Hermione grimly.
‘Was there?’ said Ron blankly.
‘How about: “progress for progress's sake must be discouraged"? How about: “pruning wherever we find practices that ought to be prohibited"?’
‘Well, what does that mean?’ said Ron impatiently.
‘I'll tell you what it means,’ said Hermione through gritted teeth. ‘It means the Ministry's interfering at Hogwarts.’
There was a great clattering and banging all around them; Dumbledore had obviously just dismissed the school, because everyone was standing up ready to leave the Hall. Hermione jumped up, looking flustered.
‘Ron, we're supposed to show the first-years where to go!’
‘Oh yeah,’ said Ron, who had obviously forgotten. ‘Hey—hey, you lot! Midgets!’
‘Ron!’
‘Well, they are, they're titchy ...’
‘I know, but you can't call them midgets!—First-years!’ Hermione called commandingly along the table. ‘This way, please!’
A group of new students walked shyly up the gap between the Gryffindor and Hufflepuff tables, all of them trying hard not to lead the group. They did indeed seem very small; Harry was sure he had not appeared that young
when he had arrived here. He grinned at them. A blond boy next to Euan Abercrombie looked petrified; he nudged Euan and whispered something in his ear. Euan Abercrombie looked equally frightened and stole a horrified
look at Harry, who felt the grin slide off his face like Stinksap.
‘See you later,’ he said dully to Ron and Hermione and he made his way out of the Great Hall alone, doing everything he could to ignore more whispering, staring and pointing as he passed. He kept his eyes fixed ahead as he
wove his way through the crowd in the Entrance Hall, then he hurried up the marble staircase, took a couple of concealed short cuts and had soon left most of the crowds behind.
He had been stupid not to expect this, he thought angrily as he walked through the much emptier upstairs corridors. Of course everyone was staring at him; he had emerged from the Triwizard maze two months previously
clutching the dead body of a fellow student and claiming to have seen Lord Voldemort return to power. There had not been time last term to explain himself before they'd all had to go home—even if he had felt up to giving the
whole school a detailed account of the terrible events in that graveyard.
Harry had reached the end of the corridor to the Gryffindor common room and come to a halt in front of the portrait of the Fat Lady before he realised that he did not know the new password.
‘Er ...’ he said glumly, staring up at the Fat Lady, who smoothed the folds of her pink satin dress and looked sternly back at him.
‘No password, no entrance,’ she said loftily.
‘Harry, I know it!’ Someone panted up behind him and he turned to see Neville jogging towards him. ‘Guess what it is? I'm actually going to be able to remember it for once— ’ He waved the stunted little cactus he had shown
them on the train. ‘Mimbuius mimbletonia!’
‘Correct,’ said the Fat Lady, and her portrait swung open towards them like a door, revealing a circular hole in the wall behind, through which Harry and Neville now climbed.
The Gryffindor common room looked as welcoming as ever, a cosy circular tower room full of dilapidated squashy armchairs and rickety old tables. A fire was crackling merrily in the grate and a few people were warming their
hands by it before going up to their dormitories; on the other side of the room Fred and George Weasley were pinning something up on the noticeboard. Harry waved goodnight to them and headed straight for the door to the
boys’ dormitories; he was not in much of a mood for talking at the moment. Neville followed him.
Dean Thomas and Seamus Finnigan had reached the dormitory first and were in the process of covering the walls beside their beds with posters and photographs. They had been talking as Harry pushed open the door but
stopped abruptly the moment they saw him. Harry wondered whether they had been talking about him, then whether he was being paranoid.
‘Hi,’ he said, moving across to his own trunk and opening it.
‘Hey, Harry,’ said Dean, who was putting on a pair of pyjamas in the West Ham colours. ‘Good holiday?’
‘Not bad,’ muttered Harry, as a true account of his holiday would have taken most of the night to relate and he could not face it. ‘You?’
‘Yeah, it was OK,’ chuckled Dean. ‘Better than Seamus's, anyway, he was just telling me.’
cheap uggs
louis vuitton handbags
gucci shoes
chanel
uggs
‘I said illuminating, not enjoyable,’ said Hermione. ‘It explained a lot.’
‘Did it?’ said Harry in surprise. ‘Sounded like a load of waffle to me.’
There was some important stuff hidden in the waffle,’ said Hermione grimly.
‘Was there?’ said Ron blankly.
‘How about: “progress for progress's sake must be discouraged"? How about: “pruning wherever we find practices that ought to be prohibited"?’
‘Well, what does that mean?’ said Ron impatiently.
‘I'll tell you what it means,’ said Hermione through gritted teeth. ‘It means the Ministry's interfering at Hogwarts.’
There was a great clattering and banging all around them; Dumbledore had obviously just dismissed the school, because everyone was standing up ready to leave the Hall. Hermione jumped up, looking flustered.
‘Ron, we're supposed to show the first-years where to go!’
‘Oh yeah,’ said Ron, who had obviously forgotten. ‘Hey—hey, you lot! Midgets!’
‘Ron!’
‘Well, they are, they're titchy ...’
‘I know, but you can't call them midgets!—First-years!’ Hermione called commandingly along the table. ‘This way, please!’
A group of new students walked shyly up the gap between the Gryffindor and Hufflepuff tables, all of them trying hard not to lead the group. They did indeed seem very small; Harry was sure he had not appeared that young
when he had arrived here. He grinned at them. A blond boy next to Euan Abercrombie looked petrified; he nudged Euan and whispered something in his ear. Euan Abercrombie looked equally frightened and stole a horrified
look at Harry, who felt the grin slide off his face like Stinksap.
‘See you later,’ he said dully to Ron and Hermione and he made his way out of the Great Hall alone, doing everything he could to ignore more whispering, staring and pointing as he passed. He kept his eyes fixed ahead as he
wove his way through the crowd in the Entrance Hall, then he hurried up the marble staircase, took a couple of concealed short cuts and had soon left most of the crowds behind.
He had been stupid not to expect this, he thought angrily as he walked through the much emptier upstairs corridors. Of course everyone was staring at him; he had emerged from the Triwizard maze two months previously
clutching the dead body of a fellow student and claiming to have seen Lord Voldemort return to power. There had not been time last term to explain himself before they'd all had to go home—even if he had felt up to giving the
whole school a detailed account of the terrible events in that graveyard.
Harry had reached the end of the corridor to the Gryffindor common room and come to a halt in front of the portrait of the Fat Lady before he realised that he did not know the new password.
‘Er ...’ he said glumly, staring up at the Fat Lady, who smoothed the folds of her pink satin dress and looked sternly back at him.
‘No password, no entrance,’ she said loftily.
‘Harry, I know it!’ Someone panted up behind him and he turned to see Neville jogging towards him. ‘Guess what it is? I'm actually going to be able to remember it for once— ’ He waved the stunted little cactus he had shown
them on the train. ‘Mimbuius mimbletonia!’
‘Correct,’ said the Fat Lady, and her portrait swung open towards them like a door, revealing a circular hole in the wall behind, through which Harry and Neville now climbed.
The Gryffindor common room looked as welcoming as ever, a cosy circular tower room full of dilapidated squashy armchairs and rickety old tables. A fire was crackling merrily in the grate and a few people were warming their
hands by it before going up to their dormitories; on the other side of the room Fred and George Weasley were pinning something up on the noticeboard. Harry waved goodnight to them and headed straight for the door to the
boys’ dormitories; he was not in much of a mood for talking at the moment. Neville followed him.
Dean Thomas and Seamus Finnigan had reached the dormitory first and were in the process of covering the walls beside their beds with posters and photographs. They had been talking as Harry pushed open the door but
stopped abruptly the moment they saw him. Harry wondered whether they had been talking about him, then whether he was being paranoid.
‘Hi,’ he said, moving across to his own trunk and opening it.
‘Hey, Harry,’ said Dean, who was putting on a pair of pyjamas in the West Ham colours. ‘Good holiday?’
‘Not bad,’ muttered Harry, as a true account of his holiday would have taken most of the night to relate and he could not face it. ‘You?’
‘Yeah, it was OK,’ chuckled Dean. ‘Better than Seamus's, anyway, he was just telling me.’
cheap uggs
louis vuitton handbags
gucci shoes
chanel
uggs
Wednesday, November 10, 2010
Support the Employee Free Choice Act
Author：佚名 Source：none Hits：110 UpdateTime：2008-10-19 1:35:21
The Employee Free Choice Act (H.R. 800, S. 1041) would amend the National Labor Relations Act by allowing the certification of a union as the bargaining representative of a unit of employees if the National Labor Relations Board (NLRB) finds that a majority of these employees signed authorization cards designating a particular union as their bargaining representative.
Under the current system, if 30% of potential members sign authorization cards designating a union as their bargaining representative, an NLRB supervised election would take place. Employers currently have the option of allowing their employees to choose a union based on the submission of authorization cards signed by a majority of employees. The Employee Free Choice Act would create a mandatory card check system.
In addition to establishing a card check system based on the submission of authorization cards by a majority of employees, the Employee Free Choice Act also establishes mediation and arbitration procedures in the event that there is a deadlock between the employer and the union in regard to the negotiation of a first contract.
It should be noted by labor union members and working people that the passage of the Employee Free Choice Act is one of the top priorities of organized labor. The adoption of this legislation will make it easier for working people to join labor unions by minimizing employer coercion and intimidation against employees who are involved in organizing drives or who simply want to join a union.
The current system is badly broken because it takes weeks or even months for the NLRB to organize elections. During that time, employers frequently use their power to lobby against unionization. It is not uncommon for employers to go beyond lobbying and resort to more coercive tactics i.e. predicting future plant closures should their employees unionize, or telling employees that they will be replaced should they unionize and go on strike. It has become increasingly common for employers to fire employees who are involved in organizing efforts. In fact, employees are fired in one quarter of private sector union organizing drives (source: AFL-CIO http://www.aflcio.org/joinaunion).
Finally, the Employee Free Choice Act is necessary to reverse the decline in the standard of living of American workers. During the Bush years, wages have stagnated. Only 38% of Americans say that there families are getting ahead. Fewer than a quarter of American believe that the next generations standard of living will be better than todays standard of living. Six million fewer Americans have health insurance now than in in 1995 (source: Testimony of Nancy Schiffer, Associate General Counsel, AFL-CIO, before the Subcommittee of Health, Employment, Labor and Pensions, U.S. House, February 8, 2007).
The value of collective bargaining can be clearly illustrated by the following statistics: union workers earn 30% more than non-union workers. Women who belong to unions earn 31% more than women who do not. African Americans who belong to unions earn 36% more than non-unionized African American workers. Finally, latinos who are unionized earn 46% more than those latino workers who do not belong to a union (source: Testimony of Nancy Schiffer, Associate General Counsel, AFL-CIO, before the Subcommittee of Health, Employment, Labor and Pensions, U.S. House, February 8, 2007).
It is generally anticipated that the Democrats will gain seats in congress after this Novembers congressional elections. Hopefully, with solidly Democratic majorities in both houses of congress and the election of Barack Obama as president, the Employee Free Choice Act will be enacted into law after languishing in the Senate since it was filibustered by the Republicans on June 26, 2007 and the Democrats lacked the votes (60) to cut off debate.
Please vote for Barack Obama for president and for pro-Employee Free Choice Act Democratic candidates for congress. Once they take office, urge them to support the Employee Free Choice Act.
The Employee Free Choice Act (H.R. 800, S. 1041) would amend the National Labor Relations Act by allowing the certification of a union as the bargaining representative of a unit of employees if the National Labor Relations Board (NLRB) finds that a majority of these employees signed authorization cards designating a particular union as their bargaining representative.
Under the current system, if 30% of potential members sign authorization cards designating a union as their bargaining representative, an NLRB supervised election would take place. Employers currently have the option of allowing their employees to choose a union based on the submission of authorization cards signed by a majority of employees. The Employee Free Choice Act would create a mandatory card check system.
In addition to establishing a card check system based on the submission of authorization cards by a majority of employees, the Employee Free Choice Act also establishes mediation and arbitration procedures in the event that there is a deadlock between the employer and the union in regard to the negotiation of a first contract.
It should be noted by labor union members and working people that the passage of the Employee Free Choice Act is one of the top priorities of organized labor. The adoption of this legislation will make it easier for working people to join labor unions by minimizing employer coercion and intimidation against employees who are involved in organizing drives or who simply want to join a union.
The current system is badly broken because it takes weeks or even months for the NLRB to organize elections. During that time, employers frequently use their power to lobby against unionization. It is not uncommon for employers to go beyond lobbying and resort to more coercive tactics i.e. predicting future plant closures should their employees unionize, or telling employees that they will be replaced should they unionize and go on strike. It has become increasingly common for employers to fire employees who are involved in organizing efforts. In fact, employees are fired in one quarter of private sector union organizing drives (source: AFL-CIO http://www.aflcio.org/joinaunion).
Finally, the Employee Free Choice Act is necessary to reverse the decline in the standard of living of American workers. During the Bush years, wages have stagnated. Only 38% of Americans say that there families are getting ahead. Fewer than a quarter of American believe that the next generations standard of living will be better than todays standard of living. Six million fewer Americans have health insurance now than in in 1995 (source: Testimony of Nancy Schiffer, Associate General Counsel, AFL-CIO, before the Subcommittee of Health, Employment, Labor and Pensions, U.S. House, February 8, 2007).
The value of collective bargaining can be clearly illustrated by the following statistics: union workers earn 30% more than non-union workers. Women who belong to unions earn 31% more than women who do not. African Americans who belong to unions earn 36% more than non-unionized African American workers. Finally, latinos who are unionized earn 46% more than those latino workers who do not belong to a union (source: Testimony of Nancy Schiffer, Associate General Counsel, AFL-CIO, before the Subcommittee of Health, Employment, Labor and Pensions, U.S. House, February 8, 2007).
It is generally anticipated that the Democrats will gain seats in congress after this Novembers congressional elections. Hopefully, with solidly Democratic majorities in both houses of congress and the election of Barack Obama as president, the Employee Free Choice Act will be enacted into law after languishing in the Senate since it was filibustered by the Republicans on June 26, 2007 and the Democrats lacked the votes (60) to cut off debate.
Please vote for Barack Obama for president and for pro-Employee Free Choice Act Democratic candidates for congress. Once they take office, urge them to support the Employee Free Choice Act.
Tuesday, November 9, 2010
Some Bonsai Trees For Sale
Author：佚名 Source：none Hits：88 UpdateTime：2008-10-19 1:07:57
A Japanese art of growing miniature container-grown trees, bonsai actually originated from China and spread to Japan and Korea. Far from the common notion that the bonsai is a kind of genetically small tree, a bonsai tree
is actually a normal tree that is kept small by continued root pruning and regular repotting.
The art of Japanese Bonsai is centered on the principle that the tree must give a picture of "heaven and earth in one container." A good Bonsai should possess the three forces of truth, essence, and beauty. Therefore, the
goal is to make it look natural and must never show a touch of human intervention. It is because of this aesthetic sense found in bonsai that it became popular and very appealing. This is why it isn't surprising that growing
bonsai turned out to be a good business venture.
There are now more people buying and growing their bonsai trees. Aside from the fact it is a good hobby, it is also an interesting and unique piece of decoration for your family room, living room, and perhaps even for your
kitchen. Since there are a variety of bonsai plants available, you can choose the flowering type contained in an ornate ceramic pot. It will be a great looking home dcor or an office accent.
Bonsai can also be sold as gifts. People are now considering bonsai as a great gift idea. Because of the time and age aspect of bonsai, it is a sweet and romantic present especially for those celebrating their wedding
anniversaries or their birthdays. Finding a bonsai tree that equals the age of a marriage or any annually celebrated occasion is truly a unique and thoughtful way of commemorating an event.
Growing bonsai is a good hobby. According to some studies about horticultural therapy, it provides a therapeutic relief from known and idiosyncratic illnesses. Some people have testimonials saying that it helps their anxiety. It
is known to have a holistic medical effect of relieving pain and reducing stress. It is also found to relax the mood and sooth tense muscles while giving an overall sense of well-being, thereby improving self-esteem.
While others have their personal reasons for having a bonsai, a bonsai artist's primary fulfillment is to create a well-manicured and creatively molded bonsai tree. Some hobbyists are greatly interested in joining exhibits and
contests to showcase their best bonsai trees.
Obviously, there is a demand for these wonderful dwarfed trees. These are some of the reasons why growing and propagating bonsai trees to augment the thriving market of bonsai trees is a savvy endeavor.
uggs
chanel 2.55
burberry outlet
coach outlet
A Japanese art of growing miniature container-grown trees, bonsai actually originated from China and spread to Japan and Korea. Far from the common notion that the bonsai is a kind of genetically small tree, a bonsai tree
is actually a normal tree that is kept small by continued root pruning and regular repotting.
The art of Japanese Bonsai is centered on the principle that the tree must give a picture of "heaven and earth in one container." A good Bonsai should possess the three forces of truth, essence, and beauty. Therefore, the
goal is to make it look natural and must never show a touch of human intervention. It is because of this aesthetic sense found in bonsai that it became popular and very appealing. This is why it isn't surprising that growing
bonsai turned out to be a good business venture.
There are now more people buying and growing their bonsai trees. Aside from the fact it is a good hobby, it is also an interesting and unique piece of decoration for your family room, living room, and perhaps even for your
kitchen. Since there are a variety of bonsai plants available, you can choose the flowering type contained in an ornate ceramic pot. It will be a great looking home dcor or an office accent.
Bonsai can also be sold as gifts. People are now considering bonsai as a great gift idea. Because of the time and age aspect of bonsai, it is a sweet and romantic present especially for those celebrating their wedding
anniversaries or their birthdays. Finding a bonsai tree that equals the age of a marriage or any annually celebrated occasion is truly a unique and thoughtful way of commemorating an event.
Growing bonsai is a good hobby. According to some studies about horticultural therapy, it provides a therapeutic relief from known and idiosyncratic illnesses. Some people have testimonials saying that it helps their anxiety. It
is known to have a holistic medical effect of relieving pain and reducing stress. It is also found to relax the mood and sooth tense muscles while giving an overall sense of well-being, thereby improving self-esteem.
While others have their personal reasons for having a bonsai, a bonsai artist's primary fulfillment is to create a well-manicured and creatively molded bonsai tree. Some hobbyists are greatly interested in joining exhibits and
contests to showcase their best bonsai trees.
Obviously, there is a demand for these wonderful dwarfed trees. These are some of the reasons why growing and propagating bonsai trees to augment the thriving market of bonsai trees is a savvy endeavor.
uggs
chanel 2.55
burberry outlet
coach outlet
Monday, November 8, 2010
Parkinsons Disease Medicines - Drugs For Parkinsons Disease
Author：佚名 Source：none Hits：111 UpdateTime：2008-10-19 0:49:09
Drugs for Correcting Deficiency of Dopamine
Levodopa (Lardopa)
Levodopa is the drug of first preference in the treatment of Parkinson's disease. It is a precursor of dopamine, a neurochemical, which is deficient In the brain of patients of this disase. Levodopa travels easily to the brain and gets converted into dopamine. This drug provides 50% relief in more than half the patients. There is significant improvement in muscle rigidity and akinesia but not necessarily in tremors.
Dosage: The average oral dose of levodopa is 4 g per day. It is usually started in a smaller dose of 250 mg twice daily, which is increased by 250 to 500 mg every week. It has been found that relief sets in 4 to 8 weeks when the daily dose has reached 2 to 2.5 g. These increases in the dose are continued till the maximum benefit is achieved or adverse effects appear. Once the adequate dose is found, it can be taken for several years without losing its value.
Adverse Effects: During prolonged treatment with levodopa, a distressing complication of ' onoff phenomenon' may occur, in which a person who has been showing continued improvement by taking this drug, suddenly starts behaving as though no drug is being given to him. This period ranges from an hour to half a day. The adverse effects of levodopa are common and include nausea, vomiting, orthostatic hypotension (a fall in blood pressure on sudden standing from a lying-down position), choreoathetoid movements (lip smacking, grimacing, head turning or abnormal involuntary movements of the upper or lower limbs), and occasionally toxic delirium, confusion, depression, restlessness, agitation, and hallucinations.
It is thought that the appearance of choreoathetoid movements is an indication of the maximum does that can be tolerated by a patient, but when this happens, the chances of the occurrence of an 'on-off phenomenon' also increase. It is, therefore, quite important to keep the doses as low as possible to avoid the occurrence of the adverse effects of choreoathetoid movements.
Precautions
The drug should not be taken on an empty stomach.
Patients who show a pronounced decrease in blood pressure on standing up from a lying down position should be protected from the possibility of fainting. They should be made to wear tight long socks and occasionally given small amounts of ephedrine.
The does should be reduced as soon as there appearance of choreoathetoid movements.
These agents should be used cautiously in patients suffering from liver or kidney disease.
The dose should be reduced if psychological symptoms persist.
Vitamin B6 reverses the effects of levodopa. Avoid use of B complex preparations which invariably contain Vitamin B6.
Anti-psychotic drugs may make levodopa ineffective, if administered simultaneously.
Drugs for Correcting Deficiency of Dopamine
Levodopa (Lardopa)
Levodopa is the drug of first preference in the treatment of Parkinson's disease. It is a precursor of dopamine, a neurochemical, which is deficient In the brain of patients of this disase. Levodopa travels easily to the brain and gets converted into dopamine. This drug provides 50% relief in more than half the patients. There is significant improvement in muscle rigidity and akinesia but not necessarily in tremors.
Dosage: The average oral dose of levodopa is 4 g per day. It is usually started in a smaller dose of 250 mg twice daily, which is increased by 250 to 500 mg every week. It has been found that relief sets in 4 to 8 weeks when the daily dose has reached 2 to 2.5 g. These increases in the dose are continued till the maximum benefit is achieved or adverse effects appear. Once the adequate dose is found, it can be taken for several years without losing its value.
Adverse Effects: During prolonged treatment with levodopa, a distressing complication of ' onoff phenomenon' may occur, in which a person who has been showing continued improvement by taking this drug, suddenly starts behaving as though no drug is being given to him. This period ranges from an hour to half a day. The adverse effects of levodopa are common and include nausea, vomiting, orthostatic hypotension (a fall in blood pressure on sudden standing from a lying-down position), choreoathetoid movements (lip smacking, grimacing, head turning or abnormal involuntary movements of the upper or lower limbs), and occasionally toxic delirium, confusion, depression, restlessness, agitation, and hallucinations.
It is thought that the appearance of choreoathetoid movements is an indication of the maximum does that can be tolerated by a patient, but when this happens, the chances of the occurrence of an 'on-off phenomenon' also increase. It is, therefore, quite important to keep the doses as low as possible to avoid the occurrence of the adverse effects of choreoathetoid movements.
Precautions
The drug should not be taken on an empty stomach.
Patients who show a pronounced decrease in blood pressure on standing up from a lying down position should be protected from the possibility of fainting. They should be made to wear tight long socks and occasionally given small amounts of ephedrine.
The does should be reduced as soon as there appearance of choreoathetoid movements.
These agents should be used cautiously in patients suffering from liver or kidney disease.
The dose should be reduced if psychological symptoms persist.
Vitamin B6 reverses the effects of levodopa. Avoid use of B complex preparations which invariably contain Vitamin B6.
Anti-psychotic drugs may make levodopa ineffective, if administered simultaneously.
OxyContin Addiction Is Creating Heroin Addicts
Author：佚名 Source：none Hits：146 UpdateTime：2008-10-19 0:49:11
In the last year or two, Ohio has seen a significant increase in heroin addiction and the deaths, crime, illness and ruined lives that go with it. Why the sudden problem? Some experts feel its largely due to prescription drug addiction and abuse, especially OxyContin addiction and addiction to other opiate painkillers.
The OxyContin addiction problem started years ago in Ohio and other Appalachian areas as well as across America - when Purdue Pharma let loose with their new, safer painkiller. According to Purdue, it was less addictive, less likely to be abused, and less likely to cause withdrawal symptoms than other opiate drugs.
Doctors and patients alike, duped by the claims, made a beeline for OxyContin only to find out years later - after addiction and abuse had become rampant, after many people had died, after thousands who were unable to endure the pain of withdrawal found they couldnt get off the drug - that Purdue had lied. In 2007, Purdue pled guilty to felony charges and was fined $634 million.
Years after the carnage began, with Purdue still thriving after paying a fine that was less than the profit they made on the drug, OxyContin addiction continues to rage like an angry bull through America. But, now, its harder to get. Doctors, knowing the truth, are less inclined to prescribe it and the drug is being stolen by health care employees, pharmacies are being robbed, addicts (and dealers who intend to sell the drug to others) are going from doctor to doctor feigning illness so they can get multiple prescriptions, and the price of OxyContin on the street has skyrocketed.
Whats the alternative? Heroin. Its cheaper, its easier to get, and the horror stories are starting to fill the news. College students found dead in bathtubs, a 67-year-old woman dealing narcotics, a homeless woman dumping her stillborn baby in the trash for fear of prosecution when its found out she was using heroin while pregnant.
Our prison population has swelled with OxyContin and heroin-related crime, and thousands of lives have been ruined.
If we caught the 9/11 terrorists, would we accept $634 million as restitution? Would we fail to incarcerate them? Would we allow them to continue to operate as a cohesive group so they could go about their business? Would we allow them to continue selling and profiting from the same wares that ruined the lives of so many?
Not likely. But OxyContin addiction continues to rage, Purdue continues to profit, and now heroin addiction is added to the mix.
We spend billions fighting the war on terrorism but still support the continued operation of terrorists on our own soil. We accept their taxes, their bribes, their political contributions, and their votes, and treat them like upstanding Americans with our best interests at heart. Whats wrong with this picture?
If you or someone you care about already has a problem with OxyContin addiction or abuse, get them into a drug addiction treatment center for OxyContin rehab as soon as possible. OxyContin addiction is bad enough, but we now have even more proof that it can lead to heroin addiction. Which is uglier, still.
In the last year or two, Ohio has seen a significant increase in heroin addiction and the deaths, crime, illness and ruined lives that go with it. Why the sudden problem? Some experts feel its largely due to prescription drug addiction and abuse, especially OxyContin addiction and addiction to other opiate painkillers.
The OxyContin addiction problem started years ago in Ohio and other Appalachian areas as well as across America - when Purdue Pharma let loose with their new, safer painkiller. According to Purdue, it was less addictive, less likely to be abused, and less likely to cause withdrawal symptoms than other opiate drugs.
Doctors and patients alike, duped by the claims, made a beeline for OxyContin only to find out years later - after addiction and abuse had become rampant, after many people had died, after thousands who were unable to endure the pain of withdrawal found they couldnt get off the drug - that Purdue had lied. In 2007, Purdue pled guilty to felony charges and was fined $634 million.
Years after the carnage began, with Purdue still thriving after paying a fine that was less than the profit they made on the drug, OxyContin addiction continues to rage like an angry bull through America. But, now, its harder to get. Doctors, knowing the truth, are less inclined to prescribe it and the drug is being stolen by health care employees, pharmacies are being robbed, addicts (and dealers who intend to sell the drug to others) are going from doctor to doctor feigning illness so they can get multiple prescriptions, and the price of OxyContin on the street has skyrocketed.
Whats the alternative? Heroin. Its cheaper, its easier to get, and the horror stories are starting to fill the news. College students found dead in bathtubs, a 67-year-old woman dealing narcotics, a homeless woman dumping her stillborn baby in the trash for fear of prosecution when its found out she was using heroin while pregnant.
Our prison population has swelled with OxyContin and heroin-related crime, and thousands of lives have been ruined.
If we caught the 9/11 terrorists, would we accept $634 million as restitution? Would we fail to incarcerate them? Would we allow them to continue to operate as a cohesive group so they could go about their business? Would we allow them to continue selling and profiting from the same wares that ruined the lives of so many?
Not likely. But OxyContin addiction continues to rage, Purdue continues to profit, and now heroin addiction is added to the mix.
We spend billions fighting the war on terrorism but still support the continued operation of terrorists on our own soil. We accept their taxes, their bribes, their political contributions, and their votes, and treat them like upstanding Americans with our best interests at heart. Whats wrong with this picture?
If you or someone you care about already has a problem with OxyContin addiction or abuse, get them into a drug addiction treatment center for OxyContin rehab as soon as possible. OxyContin addiction is bad enough, but we now have even more proof that it can lead to heroin addiction. Which is uglier, still.
Thursday, November 4, 2010
Online Home Mortgage Loan - Pros and Cons You Should Know
Author：佚名 Source：none Hits：47 UpdateTime：2008-10-18 23:50:21
Home mortgage loans can be obtained from brick and mortar lending companies. As long as such lenders are established and recognized in their field, there surely will be no problem getting a home mortgage loan from them.
Are you considering getting for yourself a home mortgage loan via the internet? Would you rather find a loan online than go to a brick and mortar mortgage loan company to do the loan application personally? Before you tap on those computer keys, here are some advantages and disadvantages of getting your home mortgage loan online.
Advantages of online home mortgage loan
First of all, if you are going to use the internet in your search and acquisition of home mortgage loan, you will be surprised to find the process not only easy but very convenient. The online process is much more simplified, unlike if you are going to meet personally with some lenders who are more likely to ask for so many information.
Online home mortgage loan companies are numerous, and so they tend to compete fiercely against one another just to get you as a client. Therefore, they offer a great variety of programs as well as numerous benefits such as flexible payment terms and low interest rates.
The corresponding cost and fees that go with the application of online mortgage loans is much cheaper than that of the mortgages taken offline.
Online mortgage loan companies are more likely to be lenient to those borrowers who have bad or even non-existent credit history. Mortgage loan companies on the internet tend to offer prospective borrowers more mortgage loan alternatives especially to those with bad credit rating and having difficulty getting loans elsewhere.
One great advantage of applying for home mortgage loan online is that you immediately know if your online application is approved. This only means that you get to enjoy your loan immediately if you earn approval. On the other hand, knowing quickly if your application is disapproved means you can immediately make a move and apply with other online lenders.
Disadvantage of online home mortgage loan
One complaint about online home mortgage loans is that there are some online lenders who ask for application and other fees even when the application has yet to become approved. This rarely happens, if at all, in the real world.
There is also the problem of accountability; as the borrower, you need to be on top of the situation which can be difficult especially of you dont have a clear idea of things. And if in case, things do go wrong, like your online loan lender does not come through, its difficult to find compensation for whatever damage or problem it might have cause you. Actually, there is no specific group that you can turn to and complain when having online loan problems.
Not all online loan lenders are represented in all the US states, and so before you apply for an online home mortgage loan, be sure the state that you are in have their representative.
Home mortgage loans can be obtained from brick and mortar lending companies. As long as such lenders are established and recognized in their field, there surely will be no problem getting a home mortgage loan from them.
Are you considering getting for yourself a home mortgage loan via the internet? Would you rather find a loan online than go to a brick and mortar mortgage loan company to do the loan application personally? Before you tap on those computer keys, here are some advantages and disadvantages of getting your home mortgage loan online.
Advantages of online home mortgage loan
First of all, if you are going to use the internet in your search and acquisition of home mortgage loan, you will be surprised to find the process not only easy but very convenient. The online process is much more simplified, unlike if you are going to meet personally with some lenders who are more likely to ask for so many information.
Online home mortgage loan companies are numerous, and so they tend to compete fiercely against one another just to get you as a client. Therefore, they offer a great variety of programs as well as numerous benefits such as flexible payment terms and low interest rates.
The corresponding cost and fees that go with the application of online mortgage loans is much cheaper than that of the mortgages taken offline.
Online mortgage loan companies are more likely to be lenient to those borrowers who have bad or even non-existent credit history. Mortgage loan companies on the internet tend to offer prospective borrowers more mortgage loan alternatives especially to those with bad credit rating and having difficulty getting loans elsewhere.
One great advantage of applying for home mortgage loan online is that you immediately know if your online application is approved. This only means that you get to enjoy your loan immediately if you earn approval. On the other hand, knowing quickly if your application is disapproved means you can immediately make a move and apply with other online lenders.
Disadvantage of online home mortgage loan
One complaint about online home mortgage loans is that there are some online lenders who ask for application and other fees even when the application has yet to become approved. This rarely happens, if at all, in the real world.
There is also the problem of accountability; as the borrower, you need to be on top of the situation which can be difficult especially of you dont have a clear idea of things. And if in case, things do go wrong, like your online loan lender does not come through, its difficult to find compensation for whatever damage or problem it might have cause you. Actually, there is no specific group that you can turn to and complain when having online loan problems.
Not all online loan lenders are represented in all the US states, and so before you apply for an online home mortgage loan, be sure the state that you are in have their representative.
Subscribe to:
Posts (Atom)